????????????? ??? ?????? ????????? ???? ?? ????? ?????? ??????? ??????????? ??????????? ??? ???? ??? ????? ?????? ??????????? ????????? ?? ??????? ??? ???? ??? ????? ????? ??????? ???????.OPANA is indicated to the relief of moderate to severe acute soreness in which the usage of an opioid is acceptable.Use of opioids for an extended time frame coul